Lactate Dehydrogenase B Rabbit pAb
Cat No.: APA2951
Size:
Product Name: | Lactate Dehydrogenase B Rabbit pAb |
Cat No.: | APA2951 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Lactate Dehydrogenase B |
calculated molecular weight: | 37 kDa |
observed molecular weight: | 37 kDa |
genbank accession number: | P07195 |
gene id (ncbi): | 3945 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016] |