IL-12A Rabbit pAb
Cat No.: APA2943
Size：
| Product Name: | IL-12A Rabbit pAb |
| Cat No.: | APA2943 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human IL-12A |
| calculated molecular weight: | 25 kDa |
| observed molecular weight: | 35 kDa |
| genbank accession number: | P29459 |
| gene id (ncbi): | 3592 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | P35; CLMF; NFSK; NKSF1; IL-12A |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008] |