SIRT2 Rabbit pAb
Cat No.: APA2927
Size:
Product Name: | SIRT2 Rabbit pAb |
Cat No.: | APA2927 |
source: | Rabbit |
reactivity: | Human, Rat |
applications: | WB,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human SIRT2 |
calculated molecular weight: | 43 kDa |
observed molecular weight: | 43 kDa |
genbank accession number: | Q8IXJ6 |
gene id (ncbi): | 22933 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | SIR2; SIR2L; SIR2L2 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010] |