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CD3 epsilon Rabbit pAb

Cat No.: APA2918
Size:
Product Name: CD3 epsilon Rabbit pAb
Cat No.: APA2918
source: Rabbit
reactivity: Human
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
FC: 1:20-1:100
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human CD3 epsilon
calculated molecular weight: 23 kDa
observed molecular weight: 23 kDa
genbank accession number: P07766
gene id (ncbi): 916
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: T3E; TCRE; IMD18
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]