Met Rabbit pAb
Cat No.: APA2912
Size：
| Product Name: | Met Rabbit pAb |
| Cat No.: | APA2912 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:100 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Met |
| calculated molecular weight: | 154 kDa |
| observed molecular weight: | 145-170 kDa |
| genbank accession number: | P16056 |
| gene id (ncbi): | 17295 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HGF; HGFR; Par4; c-Met; AI838057 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. |