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Collagen VI Rabbit pAb

Cat No.: APA2910
Size:
Product Name: Collagen VI Rabbit pAb
Cat No.: APA2910
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:100
ICC/IF: 1:200
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Collagen VI
calculated molecular weight: 109 kDa
observed molecular weight: 147 kDa
genbank accession number: P12109
gene id (ncbi): 1291
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: OPLL; BTHLM1; UCHMD1
category: Primary Ab
concentration: 0.5mg/ml
background: The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]