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Dnmt1 Rabbit pAb

Cat No.: APA2906
Size:
Product Name: Dnmt1 Rabbit pAb
Cat No.: APA2906
source: Rabbit
reactivity: Human
applications: WB,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:20-1:100
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Dnmt1
calculated molecular weight: 183 kDa
observed molecular weight: 183 kDa
genbank accession number: P26358
gene id (ncbi): 1786
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; m.HsaI
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]