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DR5 Rabbit pAb

Cat No.: APA2894
Size:
Product Name: DR5 Rabbit pAb
Cat No.: APA2894
source: Rabbit
reactivity: Human
applications: WB,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human DR5
calculated molecular weight: 49 kDa
observed molecular weight: 40,49 kDa
genbank accession number: O14763
gene id (ncbi): 8795
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]