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Claudin 1 Rabbit pAb

Cat No.: APA2885
Size:
Product Name: Claudin 1 Rabbit pAb
Cat No.: APA2885
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:2000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Claudin 1
calculated molecular weight: 23 kDa
observed molecular weight: 18 kDa
genbank accession number: O95832
gene id (ncbi): 9076
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CLD1; SEMP1; ILVASC
category: Primary Ab
concentration: 0.5mg/ml
background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]