BubR1 Rabbit pAb
Cat No.: APA2860
Size:
Product Name: | BubR1 Rabbit pAb |
Cat No.: | APA2860 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human BubR1 |
calculated molecular weight: | 120 kDa |
observed molecular weight: | 130 kDa |
genbank accession number: | O60566 |
gene id (ncbi): | 701 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008] |