KAT1 Rabbit pAb
Cat No.: APA2846
Size:
Product Name: | KAT1 Rabbit pAb |
Cat No.: | APA2846 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human KAT1 |
calculated molecular weight: | 50 kDa |
observed molecular weight: | 45 kDa |
genbank accession number: | O14929 |
gene id (ncbi): | 8520 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | KAT1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009] |