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TLR1 Rabbit pAb

Cat No.: APA2839
Size:
Product Name: TLR1 Rabbit pAb
Cat No.: APA2839
source: Rabbit
reactivity: Human
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human TLR1
calculated molecular weight: 90 kDa
observed molecular weight: 90 kDa
genbank accession number: Q15399
gene id (ncbi): 7096
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: TIL; CD281; rsc786; TIL. LPRS5
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008]