Angiotensin Converting Enzyme 1 Rabbit pAb
Cat No.: APA2835
Size：
| Product Name: | Angiotensin Converting Enzyme 1 Rabbit pAb |
| Cat No.: | APA2835 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Angiotensin Converting Enzyme 1 |
| calculated molecular weight: | 150 kDa |
| observed molecular weight: | 180 kDa |
| genbank accession number: | P12821 |
| gene id (ncbi): | 1636 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DCP; ACE1; DCP1; CD143 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010] |