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HBEGF Rabbit pAb

Cat No.: APA2832
Size:
Product Name: HBEGF Rabbit pAb
Cat No.: APA2832
source: Rabbit
reactivity: Human, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
IHC: 1:20-1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human HBEGF
calculated molecular weight: 23 kDa
observed molecular weight: 23 kDa
genbank accession number: Q99075
gene id (ncbi): 1839
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DTR; DTS; DTSF; HEGFL
category: Primary Ab
concentration: 0.5mg/ml
background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.