HBEGF Rabbit pAb
Cat No.: APA2832
Size：
| Product Name: | HBEGF Rabbit pAb |
| Cat No.: | APA2832 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 IHC: 1:20-1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human HBEGF |
| calculated molecular weight: | 23 kDa |
| observed molecular weight: | 23 kDa |
| genbank accession number: | Q99075 |
| gene id (ncbi): | 1839 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DTR; DTS; DTSF; HEGFL |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. |