Kallikrein 7 Rabbit pAb
Cat No.: APA2823
Size：
| Product Name: | Kallikrein 7 Rabbit pAb |
| Cat No.: | APA2823 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Kallikrein 7 |
| calculated molecular weight: | 28 kDa |
| observed molecular weight: | 28 kDa |
| genbank accession number: | P49862 |
| gene id (ncbi): | 5650 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | hK7; SCCE; PRSS6 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011] |