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Integrin beta 7 Rabbit pAb

Cat No.: APA2568
Size:
Product Name: Integrin beta 7 Rabbit pAb
Cat No.: APA2568
source: Rabbit
reactivity: Human
applications: WB,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:20-1:100
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Integrin beta 7
calculated molecular weight: 87 kDa
observed molecular weight: 87 kDa
genbank accession number: P26010
gene id (ncbi): 3695
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ITGB7
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer--s patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]