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ATP7b Rabbit pAb

Cat No.: APA2559
Size:
Product Name: ATP7b Rabbit pAb
Cat No.: APA2559
source: Rabbit
reactivity: Human
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human ATP7b
calculated molecular weight: 157 kDa
observed molecular weight: 157 kDa
genbank accession number: P35670
gene id (ncbi): 540
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: WD; PWD; WC1; WND
category: Primary Ab
concentration: 0.5mg/ml
background: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008]