ALK-1 Rabbit pAb
Cat No.: APA2520
| Product Name: | ALK-1 Rabbit pAb |
| Cat No.: | APA2520 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human ALK-1 |
| calculated molecular weight: | 56 kDa |
| observed molecular weight: | 56 kDa |
| genbank accession number: | P37023 |
| gene id (ncbi): | 94 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] |
