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HLA-DQA1 Rabbit pAb

Cat No.: APA2518
Size:
Product Name: HLA-DQA1 Rabbit pAb
Cat No.: APA2518
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
IHC: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human HLA-DQA1
calculated molecular weight: 28 kDa
observed molecular weight: 28-35 kDa
genbank accession number: P01909
gene id (ncbi):
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DC-1 alpha chain; DC-alpha; HLA-DCA; MHC class II DQA1
category: Primary Ab
concentration: 0.5mg/ml
background: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.