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LOX 1 Rabbit pAb

Cat No.: APA2516
Size:
Product Name: LOX 1 Rabbit pAb
Cat No.: APA2516
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human LOX 1
calculated molecular weight: 31 kDa
observed molecular weight: 50 kDa
genbank accession number: P78380
gene id (ncbi): 4973
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: LOX1; LOXIN; SLOX1; CLEC8A; SCARE1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer--s disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]