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Brk Rabbit pAb

Cat No.: APA2515
Size:
Product Name: Brk Rabbit pAb
Cat No.: APA2515
source: Rabbit
reactivity: Human
applications: WB,IHC,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:100
FC: 1:100
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Brk
calculated molecular weight: 52 kDa
observed molecular weight: 52 kDa
genbank accession number: Q13882
gene id (ncbi): 5753
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PTK6
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]