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SORL1 Rabbit pAb

Cat No.: APA2500
Size:
Product Name: SORL1 Rabbit pAb
Cat No.: APA2500
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:100-1:500
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human SORL1
calculated molecular weight: 248 kDa
observed molecular weight: 248 kDa
genbank accession number: Q92673
gene id (ncbi): 6653
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer--s disease. [provided by RefSeq, Feb 2016]