MVK Rabbit pAb
Cat No.: APA2442
Size：
| Product Name: | MVK Rabbit pAb |
| Cat No.: | APA2442 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human MVK |
| calculated molecular weight: | 43 kDa |
| observed molecular weight: | 43 kDa |
| genbank accession number: | Q03426 |
| gene id (ncbi): | 4598 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | MK; LRBP; MVLK; POROK3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |