GTPBP4 Rabbit pAb
Cat No.: APA2340
Size：
| Product Name: | GTPBP4 Rabbit pAb |
| Cat No.: | APA2340 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:50 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human GTPBP4/NOG1 |
| calculated molecular weight: | 74 kDa |
| observed molecular weight: | 80 kDa |
| genbank accession number: | Q9BZE4 |
| gene id (ncbi): | 23560 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NGB; CRFG; NOG1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. --Active-- in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008] |