CCR3 Rabbit pAb
Cat No.: APA2334
Size：
| Product Name: | CCR3 Rabbit pAb |
| Cat No.: | APA2334 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human CCR3 |
| calculated molecular weight: | 41 kDa |
| observed molecular weight: | |
| genbank accession number: | P51677 |
| gene id (ncbi): | 1232 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CKR3; CD193; CKR 3; CMKBR3; C C CKR3; CC-CKR-3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009] |