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IMPDH2 Rabbit pAb

Cat No.: APA2317
Size:
Product Name: IMPDH2 Rabbit pAb
Cat No.: APA2317
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human IMPDH2
calculated molecular weight: 56 kDa
observed molecular weight: 56 kDa
genbank accession number: P12268
gene id (ncbi): 3615
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IMPD2; IMPDH-II
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5---monophosphate into xanthine-5---monophosphate, which is then converted into guanosine-5---monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]