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RNF14 Rabbit pAb

Cat No.: APA2305
Size:
Product Name: RNF14 Rabbit pAb
Cat No.: APA2305
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human RNF14
calculated molecular weight: 54 kDa
observed molecular weight: 54 kDa
genbank accession number: Q9UBS8
gene id (ncbi): 9604
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ARA54; HFB30; TRIAD2; HRIHFB2038
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]