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BNP Rabbit pAb

Cat No.: APA2249
Size:
Product Name: BNP Rabbit pAb
Cat No.: APA2249
source: Rabbit
reactivity: Human
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human BNP
calculated molecular weight: 15 kDa
observed molecular weight: 30 kDa
genbank accession number: P16860
gene id (ncbi): 4879
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BNP
category: Primary Ab
concentration: 0.5mg/ml
background: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein--s biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]