IRF3 Rabbit pAb
Cat No.: APA2244
| Product Name: | IRF3 Rabbit pAb |
| Cat No.: | APA2244 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:50 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human IRF3 |
| calculated molecular weight: | 47 kDa |
| observed molecular weight: | 47 kDa |
| genbank accession number: | Q14653 |
| gene id (ncbi): | 3661 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | IIAE7 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important in the innate immune response against DNA and RNA viruses. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2020] |
