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SPAK Rabbit pAb

Cat No.: APA2205
Size:
Product Name: SPAK Rabbit pAb
Cat No.: APA2205
source: Rabbit
reactivity: Human
applications: WB,IHC,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human SPAK
calculated molecular weight: 60 kDa
observed molecular weight: 65 kDa
genbank accession number: Q9UEW8
gene id (ncbi): 27347
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DCHT; PASK; SPAK
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]