RASSF1 Rabbit pAb
Cat No.: APA2204
Size：
| Product Name: | RASSF1 Rabbit pAb |
| Cat No.: | APA2204 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human RASSF1 |
| calculated molecular weight: | 39 kDa |
| observed molecular weight: | 39 kDa |
| genbank accession number: | Q9NS23 |
| gene id (ncbi): | 11186 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | 123F2; RDA32; NORE2A; RASSF1A; REH3P21 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011] |