Ubiquitin Conjugation Factor E4 B Rabbit pAb
Cat No.: APA2174
Size：
| Product Name: | Ubiquitin Conjugation Factor E4 B Rabbit pAb |
| Cat No.: | APA2174 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human UBE4B |
| calculated molecular weight: | 146 kDa |
| observed molecular weight: | 146 kDa |
| genbank accession number: | O95155 |
| gene id (ncbi): | 10277 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | E4; UFD2; HDNB1; UBOX3; UFD2A |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |