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Toll Like Receptor 2 Rabbit pAb

Cat No.: APA2146
Size:
Product Name: Toll Like Receptor 2 Rabbit pAb
Cat No.: APA2146
source: Rabbit
reactivity: Mouse
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse TLR2
calculated molecular weight: 89 kDa
observed molecular weight: 89 kDa
genbank accession number: Q9QUN7
gene id (ncbi): 24088
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: Ly105
category: Primary Ab
concentration: 0.5mg/ml
background: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) (PubMed:15690042). May also promote apoptosis in response to lipoproteins (By similarity).