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GRK2 Rabbit pAb

Cat No.: APA2145
Size:
Product Name: GRK2 Rabbit pAb
Cat No.: APA2145
source: Rabbit
reactivity: Human
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human GRK2
calculated molecular weight: 80 kDa
observed molecular weight: 80 kDa
genbank accession number: P25098
gene id (ncbi): 156
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BARK1; ADRBK1; BETA-ARK1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer--s disease. [provided by RefSeq, Sep 2017]