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Keap1 Rabbit pAb

Cat No.: APA2106
Size:
Product Name: Keap1 Rabbit pAb
Cat No.: APA2106
source: Rabbit
reactivity: Human, Mouse
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Keap1
calculated molecular weight: 70 kDa
observed molecular weight: 60-64 kDa
genbank accession number: Q14145
gene id (ncbi): 9817
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: INrf2; KLHL19
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]