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Caspase-7 Rabbit pAb

Cat No.: APA2103
Size:
Product Name: Caspase-7 Rabbit pAb
Cat No.: APA2103
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:200
FC: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Caspase-7
calculated molecular weight: 34 kDa
observed molecular weight: 34 kDa
genbank accession number: P55210
gene id (ncbi): 840
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]