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Integrin alpha 4/CD49D Rabbit pAb

Cat No.: APA2065
Size:
Product Name: Integrin alpha 4/CD49D Rabbit pAb
Cat No.: APA2065
source: Rabbit
reactivity: Human, Mouse
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Integrin alpha 4/CD49D
calculated molecular weight: 115 kDa
observed molecular weight: 150,70 kDa
genbank accession number: P13612
gene id (ncbi): 3676
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IA4; CD49D
category: Primary Ab
concentration: 0.5mg/ml
background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn--s disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]