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PDK1 Rabbit pAb

Cat No.: APA2018
Size:
Product Name: PDK1 Rabbit pAb
Cat No.: APA2018
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human PDK1
calculated molecular weight: 49 kDa
observed molecular weight: 49 kDa
genbank accession number: Q15118
gene id (ncbi): 5163
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PDH kinase 1; PDHK1
category: Primary Ab
concentration: 0.5mg/ml
background: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]