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Dopamine Receptor D3/DRD3 Rabbit pAb

Cat No.: APA2003
Size:
Product Name: Dopamine Receptor D3/DRD3 Rabbit pAb
Cat No.: APA2003
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Dopamine Receptor D3/DRD3
calculated molecular weight: 44 kDa
observed molecular weight: 44 kDa
genbank accession number: P35462
gene id (ncbi): 1814
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: D3DR; ETM1; FET1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]