PCB Rabbit pAb
Cat No.: APA1985
Size：
| Product Name: | PCB Rabbit pAb |
| Cat No.: | APA1985 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human PCB |
| calculated molecular weight: | 130 kDa |
| observed molecular weight: | 130 kDa |
| genbank accession number: | P11498 |
| gene id (ncbi): | 5091 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | PCB |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5-- UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] |