Thyroid Peroxidase/TPO Rabbit pAb
Cat No.: APA1961
Size：
| Product Name: | Thyroid Peroxidase/TPO Rabbit pAb |
| Cat No.: | APA1961 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:50 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Thyroid Peroxidase/TPO |
| calculated molecular weight: | 103 kDa |
| observed molecular weight: | 103 kDa |
| genbank accession number: | P07202 |
| gene id (ncbi): | 7173 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | MSA; TPX; TDH2A |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011] |