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COMP/Cartilage oligomeric matrix protein Rabbit pAb

Cat No.: APA1946
Size:
Product Name: COMP/Cartilage oligomeric matrix protein Rabbit pAb
Cat No.: APA1946
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human COMP/Cartilage oligomeric matrix protein
calculated molecular weight: 83 kDa
observed molecular weight: 110 kDa
genbank accession number: P49747
gene id (ncbi): 1311
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MED; EDM1; EPD1; TSP5; PSACH; THBS5
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016]