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Caveolin-3 Rabbit pAb

Cat No.: APA1943
Size:
Product Name: Caveolin-3 Rabbit pAb
Cat No.: APA1943
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Caveolin-3
calculated molecular weight: 17 kDa
observed molecular weight: 17 kDa
genbank accession number: P56539
gene id (ncbi): 859
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: LQT9; MPDT; RMD2; VIP21; LGMD1C; VIP-21
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq, Jul 2008]