IL-17RA Receptor Rabbit pAb
Cat No.: APA1931
Size：
| Product Name: | IL-17RA Receptor Rabbit pAb |
| Cat No.: | APA1931 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human IL-17RA Receptor |
| calculated molecular weight: | 96 kDa |
| observed molecular weight: | 120-170 kDa |
| genbank accession number: | Q96F46 |
| gene id (ncbi): | 23765 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CD217; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014] |