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PKM Rabbit pAb

Cat No.: APA1919
Size:
Product Name: PKM Rabbit pAb
Cat No.: APA1919
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human PKM
calculated molecular weight: 58 kDa
observed molecular weight: 58 kDa
genbank accession number: P14618
gene id (ncbi): 5315
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]