Troponin I fast skeletal muscle Rabbit pAb
Cat No.: APA1880
Size：
| Product Name: | Troponin I fast skeletal muscle Rabbit pAb |
| Cat No.: | APA1880 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Troponin I fast skeletal muscle |
| calculated molecular weight: | 21 kDa |
| observed molecular weight: | 21 kDa |
| genbank accession number: | P48788 |
| gene id (ncbi): | 7136 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DA2B; FSSV; DA2B1; fsTnI; AMCD2B |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009] |