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PADI3/PAD3 Rabbit pAb

Cat No.: APA1854
Size:
Product Name: PADI3/PAD3 Rabbit pAb
Cat No.: APA1854
source: Rabbit
reactivity: Human
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human PADI3/PAD3
calculated molecular weight: 75 kDa
observed molecular weight: 75 kDa
genbank accession number: Q9ULW8
gene id (ncbi): 51702
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PAD3; PDI3; UHS1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]