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Phosphomevalonate kinase Rabbit pAb

Cat No.: APA1819
Size:
Product Name: Phosphomevalonate kinase Rabbit pAb
Cat No.: APA1819
source: Rabbit
reactivity: Human
applications: WB,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Phosphomevalonate kinase
calculated molecular weight: 22 kDa
observed molecular weight: 22 kDa
genbank accession number: Q15126
gene id (ncbi): 10654
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PMK; PMKA; PMKASE; POROK1; HUMPMKI
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]