GSTA4 Rabbit pAb
Cat No.: APA1816
Size：
| Product Name: | GSTA4 Rabbit pAb |
| Cat No.: | APA1816 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human GSTA4 |
| calculated molecular weight: | 26 kDa |
| observed molecular weight: | 26 kDa |
| genbank accession number: | O15217 |
| gene id (ncbi): | 2941 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | GTA4; GSTA4-4 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson--s disease, Alzheimer--s disease, cataract formation, and atherosclerosis. [provided by RefSeq, Jul 2008] |