fetal hemoglobin Rabbit pAb
Cat No.: APA1803
Size：
| Product Name: | fetal hemoglobin Rabbit pAb |
| Cat No.: | APA1803 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human fetal hemoglobin |
| calculated molecular weight: | 16 kDa |
| observed molecular weight: | 16 kDa |
| genbank accession number: | P69891 |
| gene id (ncbi): | 3047 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HBGA; HBGR; HBG-T2; HSGGL1; PRO2979 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5---epsilon -- gamma-G -- gamma-A -- delta -- beta--3--. [provided by RefSeq, Jul 2008] |